Borosilicated Glass Tube Vials 10ml 20ml 30ml 50ml 60ml 80ml 100ml

10ml 20ml 30ml 50ml 60ml 80ml 100ml Glass Tube Vials

Production method of glass vials
【Technical field】
The present invention relates to a method for producing glass vials, in particular pharmaceutical vials or ampoules, and glass vials produced therefrom.
【Background technique】
Glass bottles used for medicinal purposes (also called so-called "vials") consist of neutral glass, i.e. glass that can be classified as hydrolysis class 1, for which the standardized test ISO 719 (DIN 12111) is also used. grass. Especially borosilicate glasses, such as DURAN® or Fiohx® (both are registered trademarks of SCHOTT AG, Mainz) are neutral glasses.
[0003] The vials or ampoules must additionally have as low an alkali metal emission as possible, which is measured according to the standardized test ISO 4802. Glass surfaces caused by evaporation and deposition of glass components on the glass surface must be avoided, especially during thermoforming. That said, in the worst cases, this delamination can get into the contents of the vial, destroying the contents.

1. In terms of manufacturing process, medicinal glass bottles are generally divided into two categories: molded bottles and tubular bottles. Molded bottles are divided into large mouth bottles (bottle diameter greater than 30mm) and small mouth bottles. The former is used to contain powder, block and paste, and the latter is used to contain liquid.
2. According to the form of bottle mouth, it is divided into cork bottle mouth, spiral bottle mouth, crown bottle mouth, rolling bottle mouth, frosted bottle mouth, etc. According to the purpose, it is divided into "disposable bottles" discarded after one use and "recycled bottles" reused for many times.
3. It can be divided into acid bottle, medicine bottle, reagent bottle, infusion bottle, preparation bottle, etc.
Medical glass bottle display
Medicinal glass bottle display (13 photos)
4. Medicinal glass bottles can be roughly divided into the following categories according to the different uses of drugs: infusion packaging, oral liquid packaging, tablet and capsule packaging and powder injection packaging. Infusion packaging: domestic large-scale infusion packaging is mainly glass infusion bottles

Features

◆ GMP production environment

◆ Online statistical control

◆ meet ISO size and appearance AQL level

◆ detecting camera parameters and critical size defects in appearance key 77

◆ Each product can be traced to the time of delivery (DD-MM-YY), shift, machine and operator.

1, rotation speed: in a centrifuge tube expansion process, the rotational speed and diameter determined centrifugal force. When the diameter is constant, the higher the speed, the greater the centrifugal force. Under centrifugal force, the larger the diameter, the slower the speed. Thus, during the pipe expansion rate should be used as the basis to the diameter of the glass tube

2, the wall thickness is determined, and the corresponding temperature. Heating and softening the pressure in the pipe expansion process, the control diameter sizing device mainly depends on a set of synchronous rotation of the glass tube, it requires a wider range of speeds.

principle

The purpose is to eliminate permanent stress and structural imbalance in glass products. Glass is a poor thermal conductor. After the product is formed, the surface layer and the inner layer will have a temperature difference during the cooling process. When the surface layer is solidified and the inner layer is viscous, the temperature difference exists but the stress relaxation does not exist. This temperature difference occurs when the surface layer is cooled to room temperature. , The inner layer continues to cool down and shrinks, which is hindered by the surface layer to produce tensile stress, and at the same time, the surface layer produces compressive stress, which is permanent. The size and distribution of the permanent stress caused by the thermal process in each part of the product will not be uniform, therefore, it will affect the strength of the glass product, and even break by itself due to stress concentration. Annealing can eliminate harmful tension inside the glass and prevent new stress from being generated.